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. 2022 Aug 15;226(Suppl 2):S225–S235. doi: 10.1093/infdis/jiac172

Table 2.

Mean Cost per RSV Hospitalization in Infants Aged 011 Months, by Payer (2020 US$)

Commercial Payers Medicaid Payers
Study Label Sample Size, n, Original (Adjusteda) Mean (95% CI) Sample Size, n, Original (Adjusteda) Mean (95% CI)
Goldstein, 2018b [24] 981 (654) 18 083 (15 956–20 211) 2676 (1784) 10 342 (8881–11 802)
Krilov, 2020b [38] 1654 (1654) 18 473 (17 101–19 844) NA NA
Ledbetter, 2020b [39] 4842 (2556) 13 875 (11 598–16 151) 14 631 (7722) 5047 (4102–5992)
McLaurin, 2016 [40] 13 885 (11 339) 12 406 (11 739–13 073) 24 487 (19 998) 9770 (9134–10 406)
Full term, ≥37 wGA, meanc 21 362 (13 895) 12 676 (11 990–13 363) 41 794 (27 720) 8454 (7925–8984)
Ledbetter, 2020b [39] 664 (332) 20 874 (18 161–23 588) 2072 (1381) 7570 (6723–8416)
McLaurin, 2016 [40] 1292 (1034) 19 130 (16 794–21 466) 2521 (2017) 13 060 (11 660–14 460)
Late preterm, 35–36 wGA, meanc 1956 (1366) 19 554 (17 667–21 441) 4593 (3398) 10 828 (9924–11 732)
Goldstein, 2018b [24] 163 (109) 35 891 (24 770–47 012) 491 (327) 22 953 (14 819–31 087)
Krilov, 2020b [38] 186 (186) 44 088 (25 345–62 831) NA NA
Ledbetter, 2020b [39] 571 (301) 41 393 (33 768–49 017) 2029 (1071) 13 654 (11 859–15 449)
McLaurin, 2016b [40] 956 (781) 26 582 (21 837–31 327) 2349 (1918) 19 409 (17 305–21 512)
Early preterm, 29–34 wGA, meanc 1876 (1082) 30 707 (26 660–34 753) 4869 (2989) 17 347 (15 849–18 846)
Ledbetter, 2020b [39] 128 (64) 158 578 (65 062–252 097) 582 (291) 58 587 (44 715–72 459)
McLaurin, 2016 [40] 177 (142) 47 903 (20 512–75 294) 610 (488) 46 190 (29 387–62 994)
Extremely preterm, ≤28 wGA, meanc 305 (206) 82 355 (47 103–117 606) 1192 (779) 50 821 (39 087–62 556)
Overall meanc 25 499 (16 548) 15 289 (14 491–16 086) 52 448 (34 886) 10 394 (9869–10 918)

Abbreviations: CI, confidence interval; NA, not applicable; RSV, respiratory syncytial virus; wGA, weeks’ gestational age; 2020 US$, United States dollars at 2020 prices.

a

To account for unique studies that used partially overlapping datasets we adjusted the reported sample sizes by first calculating mean lives covered per year by each study, then calculating an adjusted sample size for that study for each year by removing the pro-rata share of overlapping samples based on the number of overlapping studies for that year.

b

Within-study weighted mean.

c

Across-study weighted mean included only studies that reported data for all wGA groups (Ledbetter, 2020 and McLaurin, 2016 [39, 40]) adjusted for overlapping samples.

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