. 2000 Jan 24;2000(1):CD001107. doi: 10.1002/14651858.CD001107

Comparison 1. Maintenance inhaled steroids vs placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Exacerbations requiring oral steroids	2	145	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.81 [0.21, 3.10]
2 Exacerbations requiring ER visit	1	41	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.48 [0.30, 7.40]
3 Exacerbations requiring admissions	2	135	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.14 [0.01, 2.24]
4 Duration of episodes with LRT symptoms	2	135	Mean Difference (IV, Fixed, 95% CI)	0.5 [‐1.82, 2.82]
5 Frequency of wheezing episodes per year	2	135	Mean Difference (IV, Fixed, 95% CI)	‐0.40 [‐2.40, 1.60]
6 LRT symptom severity	2	135	Mean Difference (IV, Fixed, 95% CI)	‐0.5 [‐1.43, 0.43]
7 Frequency of reductions in PEF	1	94	Mean Difference (IV, Fixed, 95% CI)	0.10 [‐0.65, 0.85]
8 Severity of reductions in PEF (min. flow)	1	94	Mean Difference (IV, Fixed, 95% CI)	12.0 [‐8.02, 32.02]
9 Duration of reductions in PEF	1	94	Mean Difference (IV, Fixed, 95% CI)	‐0.5 [‐3.41, 2.41]
10 Change in FEV1	1	88	Mean Difference (IV, Fixed, 95% CI)	0.10 [‐0.01, 0.21]