. 2020 Dec 9;12(1):1848209. doi: 10.1080/19490976.2020.1848209

Table 1.

Pathway enrichment analysis of metatranscriptomic data

Pathways	TCDF	TCDD	PCB 126	PCB 153
Tricarboxylic cycle (TCA cycle)	**		***	*
Carbon metabolism	***	**	**	*
Propanoate metabolism	***	***
Carbon fixation pathways	**		**	*
Glutathione metabolism	*		*
Amino sugar and nucleotide sugar metabolism	*	*
Pyruvate metabolism	*	**		*
Biosynthesis of amino acids	*
Pentose phosphate pathway	*	**
Biosynthesis of secondary metabolites	*
Protein export	*		*	**
Phosphotransferase system (PTS)		****	*
Fructose and mannose metabolism		**	**
Styrene degradation		**
Butanoate metabolism		**		*
Glycolysis/Gluconeogenesis		**
Purine metabolism		*
Flagellar assembly		*		*
Glycosaminoglycan degradation		*
Central carbon metabolism in cancer		*
ABC transporters		*
Lipoic acid metabolism		*		**
Bacterial chemotaxis			*	*
Homologous recombination				***
Vitamin B6 metabolism				***
Mismatch repair				**
Lipopolysaccharide biosynthesis				**
Starch and sucrose metabolism				**
DNA replication				*
Fatty acid biosynthesis				*
Pyrimidine metabolism				*
Glycine, serine and threonine metabolism				*
Base excision repair				*

Pathway enrichment analysis using the metatranscriptomic results comparing vehicle with POPs exposure. P value was calculated by a student’s t test. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001