Figure 5.
Surface Features of the Orf7a Luminal Domain
(A) Backbone worm shown in the same orientation as Figure 1B (right), and also the reverse orientation (left).
(B) The molecular surface is shown color coded by curvature to highlight local topography. The B strand and A pocket are indicated. Positions of known polymorphism are labeled. The deep groove that runs along the base of the molecule is indicated.
(C) Electrostatic potential mapped onto the accessible molecular surface; blue denotes a net positive charge (+4 kT), and red denotes a negative (−4 kT). The membrane distal face (top) is primarily acidic.