Table 2.
Δ8‐THCV did not alter number of arm crossings in the elevated plus maze
| Treatment | Arm crosses ± SEM |
|---|---|
| Saline MP, vehicle | 7.3 ± 0.8 |
| Saline MP, Δ8‐THCV (0.3 mg·kg−1) | 7.1 ± 1.2 |
| Nicotine MP, vehicle | 6.7 ± 1.3 |
| Nicotine MP, Δ8‐THCV (0.3 mg·kg−1) | 8.1 ± 1.8 |
Note. Animals undergoing spontaneous nicotine withdrawal were treated with vehicle or 0.3 mg·kg−1 Δ8‐THCV s.c., and number of crossings between arms of the plus maze was counted. Numbers are presented as means ± SEM for n = 6–8 per group.
Abbreviations: Δ8‐THCV, Δ8‐tetrahydrocannabivarin; MP, minipump.