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Skin roughness (wrinkle depth determined from the phase-shift rapid in-vivo measurement of skin (PRIMOS) skin replica) before (T0) and after (T12) intake of study products and after follow-up (FU) with test product (grey) and placebo (white), boxplot showing the mean (×), median ( 
), and max-min whiskers ( 
), absolute levels and changes are significantly different for the test product and placebo at p < 0.0001 (****). O represent outlier.
