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. 2019 Oct 1;9:14102. doi: 10.1038/s41598-019-50681-4

Figure 1.

Figure 1

Comparison of AD pathology between the common carotid artery ligation (CAL) and the control groups. (A) The expression levels of amyloid-β (Aβ), hyperphosphorylated tau (p-tau), and amyloid precursor protein (APP) were evaluated at 12 weeks after bilateral CAL using western blot analysis. (B) The Aβ levels in the frontal cortex and hippocampus are significantly higher in the CAL group than those in the control group. (C) The expression of p-tau in the temporal cortex of the CAL group is significantly higher than that in the control group. (D) There are no significant differences in APP expression between the control and the CAL group. Asterisks indicate statistical significance: *p < 0.05.

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