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. Author manuscript; available in PMC: 2018 Aug 29.
Published in final edited form as: Atherosclerosis. 2018 May 22;275:379–381. doi: 10.1016/j.atherosclerosis.2018.05.033

Table 1.

Peripheral artery disease (PAD) and evidence-based medicine.

PAD: 10 EVIDENCE-BASED FACTS
  • The risk of PAD increases substantially with age [15]

  • >50% of PAD patients are asymptomatic [14]

  • The presence of PAD is associated with a 2-fold increase in the prevalence of heart failure [16]

  • 20–30% of individuals with PAD have diabetes mellitus [17]

  • Diabetic patients have 2–4 times the risk of developing PAD, CAD, and ischemic stroke [8]

  • Smokers have 2.5 times the risk of developing PAD [3]

  • Atherosclerosis accounts for more than 90% of cases of PAD [14,18]

  • Compared to whites, the likelihood of PAD is 55% lower among Chinese and 50% greater among African Americans [19]

  • The femoral and popliteal arteries are affected in 80–90% of symptomatic PAD patients [18]

  • The prevalence of amputation in PAD patients is 3–4% [19,20]

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