Table 3.
Baseline CVRi prediction of regional cortical thickness
Brain region | Cortical thickness time point | ß | t | df | P |
---|---|---|---|---|---|
Left ITC | 24 months | −0.29 | −2.64 | 64 | 0.01Ψ |
12 months | −0.32 | −3.28 | 91 | <0.01Ψ | |
Baseline | −0.30 | −3.31 | 100 | <0.01Ψ | |
Right ITC | 12 months | −0.21 | −2.27 | 91 | 0.03 |
Left IPC | Baseline | −0.20 | −2.10 | 106 | 0.04 |
Results from linear regression of baseline and follow-up regional cortical thickness on baseline CVRi in the same region. Only amyloid-negative cases were analysed. Covariates of age, APOE genotype, body mass index, sex, baseline MMSE score, and composite FDG PET values were included. All findings remain significant under false discovery rate (FDR) of 0.10.
ΨSignificant under FDR of 0.05.