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. 2016 Oct 7;6:34989. doi: 10.1038/srep34989

Figure 2. ChIP assay for histone modifications at the Cyp1a1 promoter.

Figure 2

C57BL/6J mice were treated with 3 μg/kg of TCDD and livers were collected at 24 hrs and 40 days post-TCDD treatment. (a–c) Levels of the histone modifications H3K4me3, H4ac and H4K20me3 as assayed by ChIP assay, 24 hrs after TCDD exposure, at the promoter regions indicated. (d–f) The histone modifications H3K4me3, H4ac, and H4K20me3 as assayed by ChIP assay, 40 days after TCDD exposure. Data are expressed as mean ± SE. (n = 3). *P < 0.05, Student’s t-test.

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