16. Sleep disturbance: home palliative care versus usual care.
| Study | Measure | Analysis | Follow‐up | Significance and direction | Details |
|
Jordhøy 2000 Norway (high quality) |
EORTC QLQ‐C30 sleep disturbances item score: from 0 to 100, higher scores equal greater sleep disturbances; patient report |
Forwards from enrolment |
1 month | n.s.a SAUC intervention ‐4.7 vs. SAUC control ‐2.2 P value = 0.56 |
Intervention (n = 153): M 32 Control (n = 116): M 34 |
| 2 months | Intervention (n = 108): M 33 Control (n = 93): M 33 |
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| 4 months | Intervention (n = 71): M 32 Control (n = 65): M 28 |
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| 6 months | Differences and statistical significance not stated | Intervention (n = 56): M 28 Control (n = 52): M 32 |
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|
Rabow 2004 US (high quality) |
Medical Outcomes Study 6 sleep items measure of sleep quality and duration in preceding 4 weeks; scores: sleep quality (from 6 to 24); higher scores equal better sleep; sleep duration (0‐24 hours); patient report |
Forwards from enrolment |
6 months |
Sleep quality group main effect: favours intervention F = 4.05 P value = 0.05 group by time interaction: n.s. F = 0.14 P value = 0.71 Sleep duration group main effect: n.s. F = 2.43 P value = 0.13 group by time interaction: n.s. F = 1.98 P value = 0.17 |
Adjusted estimatesb Sleep quality Intervention (n = 50): M 11.9 Control (n = 40): M 10.0 Sleep duration Intervention (n = 50): M 6.0 Control (n = 40): M 6.3 |
| 12 months | Adjusted estimatesb Sleep quality Intervention (n = 50): M 12.5 Control (n = 40): M 11.0 Sleep duration Intervention (n = 50): M 5.8 Control (n = 40): M 6.6 |
EORTC QLQ‐C30: European Organisation for Research and Treatment of Cancer Quality of Life questionnaire; M: mean; n.s.: non‐significant; SAUC: standardised area under the curve. aThe authors calculated mean changes from baseline at one to four months after enrolment by dividing the area under the curve scores by time; differences between groups were tested by bootstrap estimation to fit regression models allowing for clustering and predictive factors. bMeans adjusted for baseline scores.