Table 2.
Effect produced by administration of the essential oil of Foeniculum vulgare and reference compounds to mice in the staircase test
Treatment | Dose (mg/kg) | Number of rearing | Number of stairs climbed |
---|---|---|---|
Vehicle | - | 19.67 ± 2.50 | 16.17 ± 6.11 |
FV | 50 | 15.00 ± 1.67 d** | 18.00 ± 4.19 e** |
FV | 100 | 13.33 ± 4.93a* d* | 13.34 ± 1.37 |
FV | 200 | 8.00 ± 3.03 (a, b, e)**. (c, f)* | 11.50 ± 3.56 |
FV | 400 | 18.33 ± 3.44 d** | 9.50 ± 4.09 a*. b** |
Diazepam | 0.5 | 14.00 ± 3.29(a*.d*) | 12.00 ± 4.56 |
Data are mean ± S.E.M, n = 6, acompared with vehicle, bto 50 mg/kg, cto 100 mg/kg, dto 200 mg/kg, eto 400 mg/kg, fto diazepam, *P < 0.05, **P < 0.01. FV = Foeniculum vulgare essential oil.