Fig. 2.
HSP90 inhibition in natural populations of Astyanax mexicanus. (A,B) HSP90 inhibition in natural populations of surface Astyanax mexicanus leads to an increase of variation in eye size (A) and orbit size (B). Eye size SD+ 83% - two sided F-test: p=8.1E-6; Bartlett’s test: p<0.001, Levene’s test: p<0.001; Orbit size SD + 108% - two sided F-test: p=3.4E-6; Bartlett’s test: p<0.001, Levene’s test p<0.001. (C) Orbit size decreases after Radicicol treatment in Tinaja cave populations (t-test: p=0.02), while change in variation is observed (SD -12%: two sided F-test: p=0.239). Control is DMSO. Asterisks in (A) and (B) compare standard deviations, while (C) compares averages.