Table 3.
Clinical Characteristics of Sedentary and Habitually Endurance-trained Postmenopausal Women who Participated in Oxidative Stress Substudy
| Variable | Placebo (n = 9) | Oral E2 (n = 10) | Trans E2 (n = 9) | Endurance-trained (n = 7) |
|---|---|---|---|---|
| Age, y | 57 ± 6 | 57 ± 4 | 57 ± 4 | 58 ± 4 |
| Menopause duration, y | 9.7 ± 8.1 | 10.0 ± 5.7 | 6.9 ± 6.0 | 5.9 ± 4.6 |
| Body mass, kg | 63.3 ± 17.9 | 79.6 ± 14.1a | 71.0 ± 13.1a | 53.8 ± 3.2 |
| BMI | 23.7 ± 5.7 | 29.3 ± 5.0a | 25.9 ± 4.2a | 19.9 ± 1.3 |
| Body fat, % | 35.0 ± 7.8a | 43.1 ± 4.5a | 39.9 ± 3.0a | 19.9 ± 4.7 |
| Systolic BP, mmHg | 118 ± 16 | 122 ± 15 | 118 ± 10 | 108 ± 10 |
| Diastolic BP, mmHg | 68 ± 11 | 71 ± 10 | 72 ± 11 | 68 ± 6 |
| Estradiol, pg/mL | 20 ± 12 | 27 ± 22 | 28 ± 17 | 28 ± 4 |
| Total cholesterol, mg/dL | 216 ± 41 | 212 ± 35 | 207 ± 28 | 204 ± 20 |
| LDL cholesterol, mg/dL | 132 ± 33 | 129 ± 27 | 134 ± 25 | 107 ± 32 |
| HDL cholesterol, mg/dL | 60 ± 17a | 57 ± 14a | 45 ± 11a | 78 ± 25 |
| Fasted insulin, μIU/mL | 5.2 ± 1.8c | 10.0 ± 4.1a | 8.0 ± 4.5 | 5.2 ± 2.1 |
| Fasted glucose, md/dL | 88 ± 6a | 94 ± 7b | 85 ± 10a | 97 ± 4 |
| Endothelin-1, pg/mL | 6.9 ± 2.0 | 7.1 ± 1.2 | 6.8 ± 1.7 | 5.8 ± 1.5 |
| VO2peak, mL/kg min | 24.3 ± 5.6a | 22.2 ± 4.5a | 22.6 ± 1.9a | 37.9 ± 5.7 |
| LTPA, MET-h/wk | 19.9 ± 15.1a | 19.5 ± 21.6a | 13.9 ± 11.8a | 66.7 ± 26.6 |
Abbreviations: BMI, body mass index; E2, estradiol; LDL, low-density lipoprotein; LTPA, leisure time physical activity; MET, metabolic equivalent; Data are mean ± SD.
a
P < .05 vs endurance-trained;
b
P < .05 vs trans E2;
c
P < .05 vs oral E2.