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. Author manuscript; available in PMC: 2013 Jul 26.
Published in final edited form as: Arch Gen Psychiatry. 2010 Dec;67(12):1211–1224. doi: 10.1001/archgenpsychiatry.2010.161

Table.

Factors in the Modern World That Increase and Decrease Inflammation

Factors Associated With Depression
That Increase Peripheral
Inflammatory Markers
Factors That Decrease
Peripheral Inflammatory
Markers
Psychosocial stress1117 Antidepressants1822
Medical illness23,24 Psychotherapy2527
Obesity2830 Electroconvulsive therapy31
Sedentary lifestyle3234 Exercise18,32,3538
Diet (eg, low ω–3:ω–6 fatty acid ratio, high-fructose sugars)3941
Diminished sleep18,4245
Social isolation18,4649
Low socioeconomic status18,5054
Female sex18,55
Smoking18,56
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