Figure 2.
Stimulus trains further differentiate corticostriatal and thalamostriatal synaptic plasticity. A, Whole-cell voltage-clamp recordings of EPSCs elicited by train stimulation (50 Hz, 5 pulses). EPSCs were fitted with five double-exponential functions (blue traces). B, Normalized EPSCs elicited by train stimulation. C, Each individual EPSC was generated and plotted based on fitted values. D, Fit EPSC amplitudes normalized to the first EPSC amplitude and plotted against stimulus number (50 Hz). Error bars indicate SEM. Asterisks indicate statistical significance.