Figure 3.
Nutrient signaling for biomass accumulation. (A) Yeasts could transmit nutrient sensing to biomass accumulation without specific growth factors. (B) A large fraction of cellular mass comprises ribosomes that accumulate in the G1- to S-phase period of the cell cycle. (C) Mammalian cells at rest use nutrients to maintain structure and homeostasis of membrane potentials. Upon stimulation with growth factors, signals from nutrients and growth factor receptors are integrated (via an AND logic gate) to stimulate cell growth or biomass accumulation.