Figure 7.
Temporal changes in levels of HB occupancy correlate with changes in DNaseI accessibility. We identified the 1-kb regions ±500 bp of the peak nucleotide of binding for each of the 400 regions most highly bound by HB at (a) stage 5 and (b) stage 9. (a) Scatter plot of the ratio of ChIP-chip scores at stage 5 over those at stage 9 (x-axis) versus the ratio of DNase-seq scores at stage 5 over those at stage 9 (y-axis). (b) Scatter plot of the ratio of ChIP-chip scores at stage 9 over those at stage 5 (x-axis) versus the ratio of DNase-seq scores at stage 9 over those at stage 5 (y-axis). The Pearson correlation coefficients (r) for each comparison are shown in the top right of each panel. See Additional file 11 for similar plots for MED.