Table 2.
Plasma amino acids
| Younger |
Older |
|||||
|---|---|---|---|---|---|---|
| Time | Basal | 60 min SNP+AA | 180 min SNP+AA | Basal | 60 min SNP+AA | 180 min SNP+AA |
| Taurine | 5.4 ± 0.2 | 6.4 ± 0.9 | 5.4 ± 1.1 | 5.9 ± 0.4 | 6.8 ± 0.6 | 6.3 ± 0.4 |
| Phosphoserine | 42.4 ± 5.9 | 57.3 ± 9.7 | 52.5 ± 7.0 | 44.3 ± 10.4 | 92.6 ± 36.1 | 58.5 ± 5.0 |
| Urea# | 1883.9 ± 835.9 | 3930.7 ± 1108.0 | 5058.3 ± 976.7 | 5075.5 ± 1025.5 | 5211.0 ± 1191.6 | 7192.1 ± 709.7 |
| Aspartic Acid** | 0.8 ± 0.8 | 24.5 ± 4.7 | 21.0 ± 3.6 | 1.0 ± 1.0 | 26.0 ± 3.1 | 29.6 ± 3.8 |
| Threonine** | 110.2 ± 10.2 | 210.6 ± 21.4 | 193.7 ± 14.3 | 130.0 ± 18.3 | 217.0 ± 20.2 | 210.6 ± 19.0 |
| Serine** | 88.9 ± 8.1 | 157.6 ± 15.4 | 141.9 ± 10.1 | 87.3 ± 6.4 | 147.5 ± 6.9 | 142.5 ± 9.1 |
| Glutamic Acid** | 66.6 ± 7.7 | 127.0 ± 15.7 | 116.2 ± 17.5 | 66.4 ± 8.7 | 150.3 ± 23.9 | 136.2 ± 18.1 |
| Glutamine# | 1118.3 ± 60.8 | 1243.5 ± 70.3 | 1143.1 ± 61.7 | 1416.9 ± 142.4 | 1315.3 ± 62.4 | 1220.2 ± 91.8 |
| Glycine* | 199.0 ± 16.6 | 292.3 ± 21.3 | 247.2 ± 18.3 | 226.3 ± 25.0 | 289.1 ± 16.0 | 256.2 ± 16.0 |
| Alanine** | 204.0 ± 12.5 | 374.3 ± 31.3 | 303.6 ± 26.4 | 232.2 ± 35.9 | 345.6 ± 37.9 | 330.9 ± 44.7 |
| Citrulline# | 28.1 ± 2.8 | 36.9 ± 3.2 | 40.3 ± 2.7 | 41.8 ± 7.6 | 47.8 ± 5.1 | 51.4 ± 4.5 |
| A Aminobutyric Acid##* | 9.6 ± 1.5 | 14.4 ± 1.4 | 17.8 ± 2.3 | 16.6 ± 2.2 | 19.3 ± 2.3 | 21.5 ± 1.8 |
| Valine#** | 149.0 ± 9.0 | 403.7 ± 38.7 | 428.8 ± 83.8 | 203.8 ± 37.1 | 457.8 ± 28.0 | 573.7 ± 32.5 |
| Methionine** | 17.3 ± 2.1 | 73.4 ± 8.9 | 71.2 ± 7.6 | 19.2 ± 3.0 | 75.2 ± 4.8 | 80.7 ± 7.0 |
| Cystine## | 8.8 ± 1.8 | 12.3 ± 2.2 | 10.0 ± 1.7 | 16.3 ± 4.2 | 17.1 ± 4.0 | 20.1 ± 2.8 |
| Isoleucine** | 38.0 ± 3.6 | 223.0 ± 26.9 | 260.4 ± 34.3 | 51.2 ± 10.9 | 249.0 ± 11.7 | 306.2 ± 22.6 |
| Leucine** | 108.2 ± 8.0 | 420.2 ± 49.2 | 494.4 ± 62.6 | 140.4 ± 22.9 | 473.0 ± 21.7 | 582.3 ± 41.8 |
| Tyrosine## | 35.8 ± 6.0 | 53.5 ± 8.5 | 45.2 ± 4.9 | 54.7 ± 7.0 | 63.3 ± 3.0 | 56.6 ± 5.4 |
| Phenylalanine** | 53.0 ± 3.2 | 117.4 ± 12.0 | 124.5 ± 13.4 | 63.2 ± 6.9 | 123.0 ± 5.2 | 139.6 ± 11.2 |
| NH3* | 63.6 ± 6.2 | 96.4 ± 7.5 | 90.5 ± 7.0 | 65.8 ± 6.8 | 96.8 ± 7.2 | 97.1 ± 5.4 |
| Ornithine** | 48.6 ± 6.2 | 90.1 ± 12.1 | 120.5 ± 22.6 | 59.4 ± 5.9 | 105.4 ± 7.9 | 147.5 ± 10.0 |
| Lysine** | 161.5 ± 15.8 | 395.2 ± 41.6 | 365.8 ± 36.5 | 183.5 ± 23.6 | 397.1 ± 12.6 | 386.7 ± 34.7 |
| 1-Methyl Histidine## | 10.6 ± 2.9 | 13.9 ± 4.1 | 11.3 ± 3.0 | 22.6 ± 4.1 | 22.3 ± 4.0 | 20.4 ± 3.4 |
| Histidine** | 63.4 ± 3.4 | 136.2 ± 12.0 | 127.1 ± 9.5 | 67.8 ± 7.7 | 130.6 ± 6.8 | 131.3 ± 10.1 |
| 3-Methyl Histidine## | 3.1 ± 0.2 | 3.2 ± 0.3 | 3.0 ± 0.3 | 5.1 ± 0.8 | 4.8 ± 0.7 | 3.8 ± 0.7 |
| Arginine** | 73.3 ± 9.5 | 299.3 ± 34.4 | 294.6 ± 30.5 | 84.4 ± 10.1 | 301.8 ± 9.7 | 313.1 ± 28.6 |
Values are expressed as means ± SE (μM). Underlined amino acids were included in the SNP+AA infusion.
#
Significant effect of age (P < 0.05).
##
Significant effect of age (P < 0.01).
*
Significant effect of time (P < 0.05).
**
Significant effect of time (P < 0.001).