FIG. 7.
Resistance to multiple translational inhibitors mediated by ubiquitin overexpression. Threefold serial dilutions of wild-type (WT) cells (SJH30), wild-type cells overexpressing ubiquitin (Ub) (SJH34), ubp6Δ (SJH31) cells, and ubp6Δ cells overexpressing ubiquitin (SJH35) were applied as spots to selective plates containing copper sulfate (100 μM) and no drug, anisomycin (50 μg/ml), or hygromycin B (100 μg/ml) (A) or tunicamycin (B) (concentrations as indicated) and grown at 30°C for 2 to 7 days.