Table-3.
Adjusted differences (± standard error) in vasoreactivity between hypertensives and normotensive participants by brain region and history of stroke
| Group | Region | Difference* | P-Value |
|---|---|---|---|
| Non-stroke group | cerebellum | 0.22±0.16 | 0.18 |
| frontal | 0.35±0.16 | 0.03 | |
| occipital | 0.29±0.16 | 0.08 | |
| parietal | 0.45±0.16 | 0.007 | |
| temporal | 0.3±0.16 | 0.07 | |
| Stroke Group | |||
| Stroke Side | cerebellum | 0.09±0.16 | 0.57 |
| frontal | 0.02±0.16 | 0.87 | |
| occipital | −0.09±0.16 | 0.55 | |
| parietal | −0.11±0.16 | 0.49 | |
| temporal | 0.05±0.16 | 0.76 | |
| Non-stroke side | cerebellum | 0.01±0.16 | 0.95 |
| frontal | −0.11±0.16 | 0.51 | |
| occipital | 0.02±0.16 | 0.91 | |
| parietal | −0.05±0.16 | 0.76 | |
| temporal | 0.06±0.16 | 0.71 |
*
Differences= Least square mean vasoreactivity in the normotensive group-hypertensive group. The differences between lobes was significant in all three groups (p<0.001 non stroke group, p=0.003 stroke side, p=0.005 opposite side). Model adjusted for age, sex, BMI, race/ethnicity, WMH/intracranial volume, and hypertensive therapy