Figure 3. Assessment of anti-adenoviral neutralizing antibody (Nabs) response in serum (A) and ascites (B).
Assessment of induced anti-adenovirus Nabs response after treatment was carried by exposing a nonreplicative luciferase expressing virus, Ad5-RGD-Luc1, to either patient serum (A) or ascites (B) prior to infection of SKOV3.ip1 cells. Following neutralization in respective samples, Ad5-RGD-Luc1 transduction efficacy was determined by a luciferase assay. Each treatment cohort's mean response is documented here in addition to a negative control represented by No Sera or No Ascites.