Figure 6.
Gene expression and DNAm for Fkbp5 in blood for cohort 2. A, A time-course change (weeks) in blood DNAm of Fkbp5 intron 1, CpG position 1 in the second cohort, in which significant methylation differences were observed between corticosterone-treated (black triangles with dashed lines) and vehicle-treated groups (white circles with solid lines) during the 4-wk treatment period and the subsequent 4-wk recovery period. B, Expression levels of Fkbp5 in blood during the 8-wk period that includes 4 wk of treatment with corticosterone and 4 wk of recovery. Asterisks indicate differences that are statistically significant (P < 0.05).