Appendix 1.
Comparing Characteristics of the SOF cohort among quartiles of mesor (mean activity level).
| Mesor (counts/min.) | |||||||
|---|---|---|---|---|---|---|---|
| OVERALL | <1796 | 1796 – 2091 | 2092 – 2386 | >=2387 | P-value | ||
| (N= 3027) | (N= 756) | (N= 757) | (N= 757) | (N= 757) | |||
| Age (y), mean (+/− SD) | 83.56 +/− 3.79 | 84.37 +/− 3.99 | 83.85 +/− 3.81 | 83.31 +/− 3.65 | 82.72 +/− 3.51 | <.0001 | |
| Body mass index (kg/m2), mean (+/− SD) | 27.04 +/− 4.99 | 28.02 +/− 5.61 | 27.49 +/− 5.06 | 26.47 +/− 4.45 | 26.23 +/− 4.59 | <.0001 | |
| African-American, (n) % | 323 (10.67) | 79 (10.45) | 68 (8.98) | 72 (9.51) | 104 (13.74) | 0.01 | |
| Any IADL impairments, (n) % | 1594 (52.96) | 525 (70.09) | 428 (56.69) | 350 (46.42) | 291 (38.7) | <.0001 | |
| History of any medical condition, (n) % | 1876 (62.08) | 540 (71.52) | 488 (64.55) | 437 (57.88) | 411 (54.37) | <.0001 | |
| History of stroke, (n) % | 398 (13.17) | 144 (19.07) | 97 (12.83) | 88 (11.64) | 69 (9.13) | <.0001 | |
| History of diabetes, (n) % | 335 (11.08) | 127 (16.82) | 89 (11.77) | 59 (7.8) | 60 (7.94) | <.0001 | |
| History of cardiovascular disease, (n) % | 1000 (33.08) | 274 (36.29) | 272 (35.98) | 245 (32.41) | 209 (27.65) | 0.0008 | |
| History of cancer, (n) % | 668 (22.11) | 173 (22.91) | 175 (23.15) | 154 (20.4) | 166 (21.99) | 0.56 | |
| Currently taking benzodiazepine, (n) % | 219 (7.24) | 65 (8.61) | 57 (7.55) | 65 (8.6) | 32 (4.23) | 0.002 | |
| Currently taking antidepressants, (n) % | 413 (13.66) | 155 (20.53) | 109 (14.44) | 78 (10.32) | 71 (9.38) | <.0001 | |
| Current sleep medication user, (n) % | 33 (1.09) | 7 (0.93) | 5 (0.66) | 8 (1.06) | 13 (1.72) | 0.24 | |
| Geriatric Depression Scale score >=6, (n) % | 355 (11.75) | 142 (18.81) | 84 (11.11) | 77 (10.2) | 52 (6.9) | <.0001 | |
| MMSE score, mean (+/− SD) | 27.86 +/− 2 | 27.62 +/− 2.13 | 27.81 +/− 2.11 | 27.94 +/− 1.93 | 28.05 +/− 1.8 | 0.0010 | |
| Current smoker, (n) % | 84 (2.78) | 36 (4.77) | 17 (2.25) | 17 (2.25) | 14 (1.85) | 0.002 | |
| Average drinks per day in past 30 days, mean (+/− SD) | 0.5 +/− 0.71 | 0.42 +/− 0.69 | 0.49 +/− 0.72 | 0.51 +/− 0.66 | 0.59 +/− 0.76 | <.0001 | |
| Average caffeine intake (mg/d), mean (+/− SD) | 151 +/− 154 | 134 +/− 149 | 141 +/− 149 | 153 +/− 148 | 175 +/− 167 | <.0001 | |
| Walks for exercise, n (%) | 1114 (37.29) | 204 (27.31) | 266 (35.47) | 309 (41.64) | 335 (44.79) | <.0001 | |
| Married, n (%) | 794 (26.27) | 125 (16.56) | 176 (23.28) | 244 (32.28) | 249 (32.94) | <.0001 | |
| Trouble sleeping in past month due to pain, n (%) | |||||||
| None | 2018 (66.75) | 494 (65.43) | 490 (64.81) | 510 (67.46) | 524 (69.31) | 0.61 | |
| <once/week | 287 (9.49) | 72 (9.54) | 72 (9.52) | 76 (10.05) | 67 (8.86) | ||
| 1–2 times/week | 333 (11.02) | 94 (12.45) | 85 (11.24) | 81 (10.71) | 73 (9.66) | ||
| 3+ times/week | 385 (12.74) | 95 (12.58) | 109 (14.42) | 89 (11.77) | 92 (12.17) | ||
| Self-reported health status, (n) % | |||||||
| Poor/very poor | 66 (2.18) | 38 (5.03) | 12 (1.59) | 7 (0.93) | 9 (1.19) | <.0001 | |
| Fair | 680 (22.49) | 222 (29.4) | 190 (25.13) | 154 (20.37) | 114 (15.08) | ||
| Good/excellent | 2277 (75.32) | 495 (65.56) | 554 (73.28) | 595 (78.7) | 633 (83.73) | ||
*
Values of p for continuous data are from ANOVA for normally distributed data and a Kruskal-Wallis test for skewed data. Values of p for categorical data are from a chi-squared test for homogeneity.
SOF=Study of Osteoporotic Fractures; MMSE=Mini-Mental State Examination; SD=standard deviation;IADL=instrumental activities of daily living.