Table 3.
Genes down-regulated by IFNs
| GenBank accession no. | Gene description | Untreated Intensity | IFN-α
|
IFN-β
|
IFN-γ
|
|||
|---|---|---|---|---|---|---|---|---|
| Intensity | Fold decrease | Intensity | Fold decrease | Intensity | Fold decrease | |||
| L77701 | COX17 | 107 | 17 | >5.3 | 60 | 0 | 28 | 3.8 |
| D86971 | KIAA0217 | 74 | 14 | >3.7 | 63 | 0 | 54 | 1.4 |
| U07000 | BCR | 77 | 24 | 3.2 | 30 | 0 | 21 | 3.7 |
| M16706 | Histone H4 | 62 | 8 | >3.1 | 1 | >3.1 | −16 | >3.1 |
| U60062 | FEZ1-T | 60 | 22 | 2.8 | 30 | 0 | 18 | >3.0 |
| U62962 | Int-6 | 237 | 121 | 2 | 473 | (2) | 158 | 1.5 |
| Z78289 | Clone 1D2 | 182 | 101 | 0 | 24 | 7.6 | 151 | 0 |
| X03562 | Insulin-like growth factor 2 | 129 | 92 | 0 | 0 | >6.4 | 115 | 0 |
| U79294 | Clone 23748 | 366 | 140 | 2.6 | 74 | 5 | 165 | 0 |
| X78817 | H. sapiens partial C1 mRNA | 206 | 145 | 0 | 46 | 4.5 | 175 | 0 |
| U76010 | Zinc transporter ZnT-3 | 469 | 289 | 0 | 118 | 4 | 296 | 0 |
| U62437 | Nicotinic acetylcholine receptor | 78 | −11 | 0 | −28 | >3.9 | 20 | 0 |
| U61232 | Tubulin-folding cofactor E | 69 | 51 | 0 | 10 | >3.5 | 51 | 0 |
| U30894 | N-sulphoglucosamine sulphohydrolase | 71 | 39 | 0 | 16 | >3.5 | 56 | 0 |
| U82311 | Unknown protein | 231 | 187 | 1.2 | 66 | 3.5 | 200 | 0 |
| X17025 | Homolog of IPP isomerase | 109 | 55 | 0 | 147 | 0 | 8 | >5.5 |
| U78798 | TRAF6 | 117 | 44 | 0 | 41 | 2.8 | 28 | 4.1 |
| Z31695 | Inositol polyphosphate 5-phosphatase | 79 | 37 | 0 | 50 | 0 | 17 | >3.9 |
| M15841 | U2 RNA-associated B antigen | 129 | 104 | 0 | 121 | 0 | 38 | 3.4 |
| X97748 | PTX3 | 90 | 63 | 0 | 107 | 0 | 26 | 3.5 |
| L33243 | Polycystic kidney disease 1 protein | 60 | 33 | 0 | 38 | 0 | 4 | >3.0 |