Figure 3. Cerebral angiogenesis identified with MRI and confocal images.
SWI of brain coronal sections shows dark areas at the ischaemic boundary (A and D, arrowheads), which match angiogenic areas detected with confocal microscopy (B and E, arrowheads). These areas show increased CBF measured with perfusion-weighted MRI (C and F, arrowheads). All images were acquired 6 weeks after stroke from rats treated with EPO (A to C) and saline (D to F). CBF=cerebral blood flow. EPO=erythropoietin. SWI=susceptibility-weighted imaging.