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. Author manuscript; available in PMC: 2010 Jul 23.
Published in final edited form as: Cell. 2009 Jul 16;138(2):389–403. doi: 10.1016/j.cell.2009.04.042

Figure 3. Interaction landscape of 75 human Dubs and their classification into topological categories.

Figure 3

(A) Heat map generated from hierarchical clustering of the 774 HCIPs for 75 Dubs. The color of the interacting protein corresponds to its DN-score.

(B) Interactions among HCIPs for each Dub were determined using CompPASS in conjunction with the STRING, BioGRID, and MINT PPI databases. The 7 topological groups based on the number of HCIPs and number of interactions among HCIPs are shown. Enlarged maps are provided in Figure S9.

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