Figure 3. Response of central metabolism to phosphoketolase over-expression during growth on a glucose medium.
A green box means that one or more isoenzymes of this reaction is down-regulated in the phosphoketolase over-expressing strain relative to the wild type. A red box indicates up-regulation. A blue box shows that some genes with this function are up-regulated while others are down-regulated. A grey box indicates that a gene could not be assigned to this function. The map was adapted from a map of A. niger metabolism published by Andersen et al [31].