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RBPJ is exchanged for RBPJL on the Rbpjl promoter during pancreatic development. ChIP analysis of PTF1a, RBPJL, and RBPJ at the proximal promoter region of Rbpjl (A) and the proximal Cpa1 promoter (B). An antibody to rabbit IgG was used to estimate background precipitation of Rbpjl promoter DNA. Arrows flanking the PTF1-binding sites in the promoters indicate the positions of the PCR primers. Error bars are SEM for three ChIPs.
