FIG. 3.
Viruses used in this study. The diagram represents the sequences of the M proteins of the viruses used in this study. Mutations in the M proteins are indicated by boxes. The tsO82 virus (number 2) is a naturally occurring mutant of the Orsay strain of VSV (number 1) containing the M51R mutation (11). The remaining viruses are recombinants isolated from VSV infectious cDNA clones, which differ only in their M genes. The M genes of the original recombinant wt (rwt) virus (3) and rM51R-M mutant (4) are derived from the San Juan strain (27, 42). The viruses containing the wt M protein from the HR strain (rHR-M virus) (5), the M51R mutation in the HR M protein (r1026-M virus) (6), and the TP2 and TP3 mutations in the HR M protein (7 and 8) were generated for this study. Sites of amino acid differences between the San Juan and HR strains are indicated by asterisks.