Abstract
1. Intracellular recordings of the end-plate current at different membrane potentials were made, using a voltage-clamp technique.
2. When the membrane potential is varied between about +40 and -120 mV, the half-decline time of the end-plate current increases from about 0·6 msec to about 1·6 msec.
3. It is suggested that the stability of receptor—mediator complex is affected by the membrane potential.
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Selected References
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