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Nuclear accumulation of GFP-IRF7 induced by LMP-1 is not inhibited by BZLF1. GFP fluorescence was detected by inverted light microscopy in 293 cells transfected with EGFP-IRF-7 (A); EGFP-IRF-7 and LMP-1 (B); EGFP-IRF-7 and BZLF-1 (C); or EGFP-IRF-7, LMP-1, and BZLF-1 (D). Subcellular localization of IRF-7 was examined 24 h after transfection. Fields of cells were scored to determine percentage of nuclear localization.
