Extended Data Fig. 11. Eliminated genes and repeats identified in the hagfish genome.
a, Plot showing the degree of germline enrichment and estimated span of all predicted repetitive elements. Previously identified elements30,33 are highlighted by coloured circles and new high-copy elements are highlighted by coloured diamonds. b, PCR validation illustrating germline enrichment and tandem repetition of predicted satellite elements. g: germline (testes) DNA used as template, s: somatic (blood) DNA used as template. c–e, Gene trees for homologues that are eliminated in both lamprey and hagfish. Gnathostome clades are highlighted in shades of green and cyclostome clades are highlighted in shades of purple. Individual germline-specific genes are highlighted in red (hagfish) or blue (lamprey). c, Tree for YTHCD2 homologues. d, Tree for WNT7 homologues. e, Tree for MSH4 homologues. f,g, Gene trees for homologues that are highly duplicated in hagfish. Gnathostome clades are highlighted in shades of green and cyclostome clades are highlighted in shades of purple. Individual germline-specific genes are highlighted in red. f, Tree for FBXL4 homologues. g, Tree for TRRAP homologues.